Cochrane is delighted to unveil the fully comprehensive edition of the *Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy. *Designed for authors, editors, and researchers involved in Cochrane Reviews and systematic evaluations of test accuracy, this invaluable resource provides an extensive guide encompassing the most advanced methodologies and best practices. Whether you’re a novice researcher or a seasoned expert, this groundbreaking Handbook equips you with the latest methodologies and expert tips, serving as an invaluable resource for conducting diagnostic test systematic reviews. This Handbook paves the way for better-informed healthcare choices, propelling us towards a future where the impact of medical tests is fully optimized.